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Finding the Truth

...Perinephric fluid collections, and Intrapulmonary shunting). A targeted treatment with FDA-approved therapies meant O’Connell’s patient “rose like Lazarus,” she says, eventually shedding the oxygen tank and leaving the hospital on her own two feet. “These are the kinds of stories that really drive me,” O’Connell says. “I’m very interested in...

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Cancer survivor donates $500,000 to USC Norris Cancer Center

...Foundation, he is on the board of Caring Bridge, is marketing committee chairman for Angel Foundation and volunteers with Imerman Angels. He hopes his efforts will benefit others. “In the blink of an eye, the world around us has and will continue to change,” Petinga said. “It’s now time to...

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Rewarding Work: Janice Lu devotes her life to making life better for breast cancer patients at USC Norris

When she was just 5 years old, Janice Lu, MD, PhD, decided to become a doctor. Her mother had just been diagnosed with breast cancer. Lu was determined from that point on to make a difference in the world of breast cancer research and treatment. “This was always what I...

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Challenge Accepted: Improving Treatment Options for Patients with Brain Cancer

...pair of trials for immunotherapy drugs, which harness the power of the body’s immune system to fight the cancer. Though immunotherapies are on the market for other types of cancer, it was long believed that immunotherapy drugs, much like chemotherapy drugs, would not pass the blood-brain barrier. But new delivery...

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USC Norris study finds herpesvirus activates RIG-I receptor to evade body’s immune system

Pinghui Feng, PhD Using herpesvirus, molecular immunologists from the University of Southern California (USC) Norris Comprehensive Cancer Center have discovered a cellular process that activates a critical immune defense against pathogens, which could have implications for developing drugs to bolster one’s immunity to infection. Some herpesvirus infections lead to cancer....

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‘State of the Cancer Center’ presentation points to growth, promising discoveries

The USC Norris Comprehensive Cancer Center had an outstanding 2016, as reported by Stephen B. Gruber, MD, PhD, MPH, USC Norris director, in his annual “State of the Cancer Center” presentation on Jan. 17. “The cancer center is flourishing,” said Gruber, professor of medicine and preventive medicine and Jane and...

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Straight to the Source

...Cancer Family Registry (CFR), the Molecular Epidemiology of Colorectal Cancer Study (MECC), the Asian Colorectal Cancer Consortium (ACCC) and the Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO). The team, which was spread across five continents, found six regions of the genetic code that are linked to a higher risk...

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Keck Medicine of USC researchers discover dual purpose of cancer drug in regulating expression of genes

Keck Medicine of USC scientists have discovered new clues about a drug instrumental in treating a certain blood cancer that may provide important targets for researchers searching for cures. The team investigated whether demethylation of gene bodies induced by the drug 5-Aza-CdR (decitabine), which is used to treat pre-leukemia, could...

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The Future of Medicine is Personalized

...information over time. When it comes to treating cancer patients, genomic testing and targeted therapies are already progressing and many new drugs, aimed at halting the progress of particular types of tumors based on genetic information, are already in the pipeline. Despite his background in research on cancer, Carpten says...

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Award-winning genomic scientist to build new department and institute

...a translational genomics team at USC, Gruber said. “Translational genomics is at the forefront of modern medicine,” he said. “Translational genomics is truly the definition of scholarship with consequence, creating the methods to bring genomic insights into patient care, where it truly makes a difference for people.” by Zen Vuong...

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