Our Program

Our Colorectal Cancer Program at USC Norris Comprehensive Cancer Center is one of the nation’s leading programs in cancer treatment and cancer genetics. We offer care for the full range of disorders affecting the colon and rectum – from more common to the most complex – providing us the broad experience to deliver colorectal cancer expertise not found elsewhere.

With access to a wealth of innovative technologies, we offer special surgical expertise, including:

  • Laparoscopically-assisted surgery
  • Ileal pouch-anal anastomosis
  • Continent ileostomy

Our specialists are changing the face of colon cancer treatment. Affiliated with a university-based research program, we are one of very few centers in the world to integrate predictive and prognostic molecular biomarker profiling. Our team has one of the most experienced minimally invasive/laparoscopic surgical teams in the nation and specializes in all forms of minimal access colon and rectal surgery, including robotic surgery. These techniques decrease recovery times and lessen pain after surgery.

Our expertise in cancer genetics allows us to genetically tailor chemotherapy treatment so it may have fewer side effects. Our medical oncologists can create a sort of genetic fingerprint of your particular cancer. Armed with genetic information, gastrointestinal oncologists can better customize treatment and offer medicines that may hold a greater potential for extending life.

Research is an active and important part of the medical oncology program, as our oncologists strive to bring the latest advancements in medicine from the laboratory to the bedside. Our program is the largest pre-clinical research program in the United States. Because of our highly specialized expertise, our patients have access to clinical trials and advanced treatment alternatives not available at other hospitals. Candidacy for clinical trials is determined on a case-by-case basis according to trial characteristics.

For more detailed information on colorectal cancer, click here to view our online health library.

Our Approach

We are dedicated to providing coordinated, comprehensive care and advancing research in the diagnosis, treatment and prevention of colorectal cancer. Patients who have colorectal cancer are treated by a multidisciplinary team of experts, including colorectal surgeons, radiation oncologists, medical oncologists, gastroenterologists, enterostomal therapists, urologists, liver surgeons, lung surgeons, geneticists, dieticians and nurse specialists.

In consultation with you and your referring physicians, our team collaborates to plan an appropriate treatment for the eradication and management of your cancer. Our team is especially sensitive to the anxieties and concerns of patients who have malignant colorectal disease. Surgeons focus on matching the extent of surgery with the extent of disease, with a goal of achieving the best result while preserving, whenever possible, quality of life.

Your team holds bi-weekly patient care conferences with multiple and diverse specialists to discuss your status and evaluate your treatment plan. The collective knowledge we gain helps us identify, monitor and adjust to new treatments to give you the best care. We also offer patients support groups and the opportunity to match with a buddy who has undergone treatment for a similar type of cancer.

Our Physicians

view more

Afsaneh Barzi, MD, PhD

Practicing Locations

  • Keck Medicine of USC - Pasadena
view more

Kyle G. Cologne, MD

Practicing Locations

  • Keck Hospital of USC
  • Keck Medicine of USC - Pasadena
  • LAC+USC Medical Center
  • USC Norris Comprehensive Cancer Center and Hospital
view more

Anthony B. El-Khoueiry, MD

Practicing Locations

  • USC Norris Comprehensive Cancer Center and Hospital
view more

Andreas M. Kaiser, MD, FACS, FASCRS

Practicing Locations

  • Keck Hospital of USC
  • USC Norris Comprehensive Cancer Center and Hospital
view more

Heinz-Josef Lenz, MD

Practicing Locations

  • USC Norris Comprehensive Cancer Center and Hospital